How Tobacco Smoke Causes Disease
The Biology and Behavioral Basis for Smoking-attributable Disease : A Report of the Surgeon GeneralBook - 2010
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Publisher: Rockville, MD : U.S. Dept. of Health and Human Services, Public Health Service, Office of the Surgeon General ; Washington, DC : For sale by the Supt. of Docs., U.S. G.P.O., 2010.
Characteristics: xv, 704 p : ill. (some col.) ; 28 cm.